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Bayes at Red Door Analytics

Portrait of speaker
Speaker: Michael Crowther and Alessandro GaspariniDate & time: Thu Apr 10 2025, 14:00-16:00 (CEST)Place: Rockefeller, Nobels väg 9Type: Seminar
This is an in-person event only. No zoom link will be provided.

Alessandro Gasparini and Michael Crowther are statisticians at Red Door Analytics.

In their talk, they will give practical examples of how they integrate Bayesian statistics in their work as statistical consultants at Red Door Analytics. Specifically, they will talk about their ongoing projects incorporating Bayesian joint modelling and advanced Bayesian survival analysis using merlin and morgana.

Abstract

Bayesian Joint Models for Longitudinal Cluster Randomised Trials with Informative Dropout

We recently introduced a frequentist joint modelling approach to account for informative dropout in longitudinal stepped wedge cluster-randomized trials (Gasparini et al., Statistics in Medicine, 2025). This approach combines a linear mixed-effects model for the longitudinal outcome of interest with a survival model for the dropout process, jointly estimating both components. We now extend this methodology to longitudinal cluster-randomized trials (a special case of the stepped wedge design) and adopt a Bayesian framework to enhance the interpretability of trial results and increase statistical power by incorporating prior knowledge or beliefs, when available. We illustrate the Bayesian joint modelling approach in practice using data from the CARING trial, a cluster-randomized controlled trial evaluating an integrated community strategy to promote maternal nutrition and paediatric outcomes in rural eastern India, where undernutrition is highly prevalent.